PO-271 Using human lung organoids to study pulmonary neuroendocrine cells

[APUD cells. The human pulmonary neuroendocrine system].

Pulmonary neuroendocrine cells and lung development: dim outlines emerge.

Lung Organoids and Their Use To Study Cell-Cell Interaction

PURPOSE OF REVIEW The lung research field has pioneered the use of organoids for the study of cell-cell interactions. RECENT FINDINGS The use of organoids for airway basal cells is routine. However, the development of organoids for the other regions of the lung is still in its infancy. Such cultures usually rely on cell-cell interactions between the stem cells and a putative niche cell for th...

A confocal microscopic study of solitary pulmonary neuroendocrine cells in human airway epithelium

BACKGROUND Pulmonary neuroendocrine cells (PNEC) are specialized epithelial cells that are thought to play important roles in lung development and airway function. PNEC occur either singly or in clusters called neuroepithelial bodies. Our aim was to characterize the three dimensional morphology of PNEC, their distribution, and their relationship to the epithelial nerves in whole mounts of adult...

Pulmonary neuroendocrine cells in chronic renal failure.

In patients with chronic renal failure, mechanical and haemodynamic changes could occur in the lungs without obvious pulmonary symptoms and findings, and their effects could pave the way to pulmonary functional disorders. Numerous studies have demonstrated that the respiratory system is a site of synthesis of many compounds, which play biological roles ascribed to hormones. The present article ...